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Dilzem may be available in the countries listed below.
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Glossary
| SPC | Summary of Product Characteristics (UK) |
Viron may be available in the countries listed below.
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Generic Name: ticagrelor (tye KA grel or)
Brand Names: Brilinta
Ticagrelor keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions.
Ticagrelor is used to lower your risk of having a stroke or serious heart problems after you have had a heart attack or severe chest pain (angina).
Ticagrelor may also be used for purposes not listed in this medication guide.
Ticagrelor keeps your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions. Because of this drug action, ticagrelor can make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.
Ticagrelor may cause you to bleed more easily, especially if you have: a history of bleeding problems, surgery or a medical emergency, a disease affecting the blood vessels in your brain, a history of stomach or intestinal bleeding, or if you are 65 or older.
severe liver disease;
any active bleeding;
stomach ulcer or bleeding; or
a history of bleeding in the brain (such as from a head injury).
To make sure you can safely take ticagrelor, tell your doctor if you have any of these other conditions:
liver disease;
asthma, COPD (chronic obstructive pulmonary disorder) or other breathing problem;
a history of stomach ulcer or colon polyps;
a history of stroke; or
a history of bleeding or blood clotting disorder.
Ticagrelor may cause you to bleed more easily, especially if you have:
a recent surgery or bleeding injury;
a disease affecting the blood vessels in your brain;
a history of stroke;
a history of bleeding problems;
a history of stomach or intestinal bleeding; or
if you are 65 or older.
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Ticagrelor should be taken together with aspirin. Follow your doctor's instructions about how much aspirin you should take.
Ticagrelor can be taken with or without food. Take the medicine at the same time each day.
If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using ticagrelor. You may need to stop using the medicine for at least 5 days before having surgery, to prevent excessive bleeding. Follow your doctor's instructions and start taking ticagrelor again as soon as possible.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
feeling light-headed or short of breath, even with mild exertion or while lying down;
nosebleed or other bleeding that will not stop;
bloody or tarry stools, blood in your urine;
coughing up blood or vomit that looks like coffee grounds;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
sudden numbness or weakness, especially on one side of the body;
sudden severe headache, confusion, problems with vision, speech, or balance;
pale skin, weakness, fever, or jaundice (yellowing of the skin or eyes); or
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin.
Less serious side effects may include:
headache, mild dizziness;
cough; or
nausea, diarrhea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medicines you use, especially:
dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
digoxin (Lanoxin);
nefazodone;
an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or telithromycin (Ketek);
antifungal medicine such as itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
a blood thinner such as warfarin (Coumadin, Jantoven);
cholesterol-lowering medications such as lovastatin (Mevacor, Altoprev, Advicor) or simvastatin (Zocor, Simcor, Vytorin);
heart or blood pressure medication such as nicardipine (Cardene) or quinidine (Quin-G);
HIV or AIDS medication such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), etravirine (Intelence), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, Kaletra), or saquinavir (Invirase); or
seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenobarbital (Solfoton), phenytoin (Dilantin), or primidone (Mysoline).
There may be other drugs that can interact with ticagrelor. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
See also: Brilinta side effects (in more detail)
